Simultaneous pancreatic and kidney transplant in adult with autosomal dominant polycystic kidney disease and type i diabetes mellitus : post surgical events and genetic review.
المصدر
Oman Medical Journal, v. 39, no. 3, p. 1-5.
مؤلف
Al-Alawiyah, Intisar.
الناشر
Oman Medical Specialty Board.
العنوان الأصلي
Simultaneous pancreatic and kidney transplant in adult with autosomal dominant polycystic kidney disease and type i diabetes mellitus : post surgical events and genetic review.
الملخص الإنجليزي
Autosomal dominant polycystic kidney disease (ADPKD) is a common inherited
condition characterized by the growth of multiple bilateral cysts in the kidneys. We
describe the case of a 35-year-old male with combined ADPKD and type 1 diabetes
mellitus with a strong family history of both. At the age of 32, he developed end-stage
kidney disease for which he underwent preemptive simultaneous pancreatic and kidney
transplant, which in turn led to multiple perioperative complications. Evaluation of
familial clustering of genetic disease is critical in genetic epidemiology and precision
medicine as it enables estimation of lifetime disease risk and early assessment as well as
detection of the disease among one’s siblings.
