Leiomyomatous lesions of the colon : two case reports with radiological features, pathological correlations, and literature review.
المصدر
Oman Medical Journal, v. 39, no. 1, e595 p. [1-6].
الناشر
Oman Medical Specialty Board.
العنوان الأصلي
Leiomyomatous lesions of the colon : two case reports with radiological features, pathological correlations, and literature review.
الملخص الإنجليزي
Colonic leiomyomatous lesions are smooth muscle tumors including both benign
leiomyoma and malignant leiomyosarcoma. They usually occur in elderly and middleaged groups. They are rare, representing 3% of all gastrointestinal leiomyomas.
Descending and sigmoid colon are the most commonly affected segments of colon.
Patients are usually asymptomatic but occasionally they may present with abdominal
pain, hemorrhage, and intestinal obstruction. Radiological findings for these lesions are
variable and overlapping with other diagnoses but usually manifest as large lesions with
lobulated margins, extra-colic growth, and heterogeneous enhancement. Final diagnosis
is achieved by tissue diagnosis in which immunohistochemistry is used to differentiate
them from other types of mesenchymal tumors like gastrointestinal stromal tumor. A
complete surgical/endoscopic resection is usually curative with an excellent prognosis
in cases of benign leiomyoma. In cases of leiomyosarcoma, post-surgical chemotherapy
and radiotherapy are usually needed with a five-year survival of about 50%. We report
the radiological findings with pathological correlation and literature review of two cases
of colonic leiomyomatous lesions that presented with nonspecific abdominal pain. The
lesions were resected surgically and confirmed histopathologically as leiomyoma and
leiomyosarcoma of the colon, respectively. To the best of our knowledge, these cases are
the first of colonic leiomyomatous lesions to be reported in Oman.
