الملخص الإنجليزي
Objectives: The aim of this study is to determine safety of
induction of labor with vaginal Prostaglandins (E2) in Grand
Multipara.
Methods: Prostaglandin E2 was used in the form of vaginal
tablets or gel in post fornix for induction as per protocol. Maternal
and fetal data collected included age, parity, and indication of
induction, bishops score, total dose of PGE2 used & complications
of induction of labor. The data was collected and analyzed using
Epi info - 6.
Results: 50% cases were induced for past dates, the ceasarean
rate was high in the induction group (19.5% ) compared to the
control (12.5% ) OR 1.69 RR 1.37(95% CI-1.07-1.75) difference
was statistically significant. Adverse neonatal outcome was found
to be similar in both groups. Special Care Baby Unit (SCBU)
admissions were 19 in the induction group and 21 in the control
group, which was not statistically significant. No severe maternal
complications were observed such as infection or uterine rupture.
Conclusion: As there were no adverse events in the study, it may
be safe to use vaginal PGE2 as method of choice for induction of
labour in grand mutipara. However, RCT for further validation of
these findings is recommended.
