الملخص الإنجليزي
From a recently instituted web-based pituitary tumour registry at Sultan Qaboos University Hospital, Oman,
this study explores the results of comprehensive clinical evaluation, hormonal levels, radiological evidence of pituitary mass lesion
using magnetic resonance (MRI) and the different treatment modalities. Methods: All patients who were diagnosed with pituitary
mass tumours in our tertiary care endocrinology clinic between January 998 and February 2006 were registered in the Oman pitui tary tumour registry. Two physicians performed hospital chart review and data entry. Results: A total of 60 entries were made into
the pituitary tumour registry. The overall mean age of the cohort was 32 ±2 years (age range 8-73 years). The majority of registrations
were female (n=4; 7%). There were 8 patients with non-functioning adenomas (50.6%), 59 with prolactinoma (36.9%) eight with
acromegaly (5%), seven with craniopharyngioma (4.4%), four with Cushing's disease (2.5%) and one with sarcoidosis (0.6%). Sub-group
analyses were done only for the subjects with the 3 most prevalent pituitary tumours (non-functioning adenomas, prolactinomas,
and acromegaly). The most prevalent symptoms are amenorrhea-galactorrhea (n=55; 37%), headache (n=3; 2%) and fatigue (n=23;
6%). The most common treatment modality was medical (n=58; 39%), followed by observation (n=56; 38%), surgery (n=3; 2%) and
surgery plus medical (n=3; 2%). None of the patients in this registry are recorded to have died. Conclusion: To our knowledge, this is
the first pituitary tumour registry in the Arabian Gulf countries using a web-based programme. This tumour registry will enable us to characterize clinical and the epidemiological features of pituitary tumours in the Sultanate of Oman
