الملخص الإنجليزي
Mixed connective tissue disease (MCTD) is a unique disorder characterized by the
presence of a high titer of anti-U1 ribonucloprotein antibody with overlapping features of
various connective tissue disorders including systemic lupus erythematosus, scleroderma,
and myositis. Severe renal or neurological involvement is unusual with this disorder. We
describe a case of biopsy-confirmed severe sensorimotor axonal polyneuropathy in a
middle-aged gentleman as his first presentation for MCTD.