الملخص الإنجليزي
Abstract
Background: Oman is currently witnessed a dramatic change in lifestyle and food choices as compared to the past, this was accompanied with an increase in the rate of morbidity and mortality from non-communicable diseases, including cardiovascular diseases (CVD). Objectives: This study was aimed to assess the nutritional and biochemical status of folate and vitamin B6 and vitamin B12 in relation to homocysteine level in newly diagnosed Omani cardiac patients. Methods and Subjects: A descriptive study approach was applied, and among 100 newly diagnosed Omani cardiac patients, only 25 cardiac (12 males and 13 females) were eligible in according to inclusion and exclusion criteria for this study. Results: Compared to reference values, the enrolled cardiac patients were overweight, had a history of hypertension, had hyperhomocysteinemia and showed significantly reduced levels of dietary intake of folate, vitamin B6 and vitamin B12 that is concomitant with low serum levels of these three nutrients. The study participants consumed high protein and saturated fats from animal sources in amount that exceeds the recommended daily dietary intake. Conclusion: Our data supports previous reports suggesting hyperhomocystenemia and low status of folate, vitamin B6 and vitamin B12 are involved in the aetiology of CVD among high risk groups.