English abstract
Flavonoids are natural antioxidants; that may prevent stress, reduce LDL cholesterol, platelet clump, and ischemic damage. Since the discovery of flavonoids as the significant natural antioxidant, they are known as biological modifiers. They can modify the human's reaction as well as ingredients. They are also instrumental in preventing the oxidative stress and free radical damage. About 25% of prescription drugs are available in the market to treat diseases are derived from nature. Numerous scientists are working with available natural resources to discover new drugs which can be used as medicine to cure or prevent different curable and incurable diseases. The scientific and medical community within the Sultanate of Oman has considered potential natural resources within the Gulf region for purpose to aid medical research. There is an abundant of unexplored plants, marine, and animal sources. Some of them have indicated potential pharmacological activity which can be used to discover new medicines to treat diseases. Ziziphus jujube (Z. jujube) is a medium size native plant which is available in Oman. It is belongs to Rhamnaceae classification and is traditionally used by the local community for the treatment of joint pain, dandruff, acne, chronic constipation, antiseptic, sedative, hypnotic and cardiac diseases. Previous studies have shown that this particular plant has various active principles which can affect biological activity. In addition, the previous research indicated that the plant extracts and isolated principles also contain significant activity. The plant has several varieties of species globally and one of the most common species is known as Z. jujube. Various biological studies have been conducted by scientists on the locally grown selected plant. However, due to lack of unavailable facilities, some of the parameters have not been able to be investigated as of yet. Therefore, the objective of this review is to summarize the previous reported phytopharmacological status of the selected plant species. Also, this review will help to encourage other scientist to continue the work on the selected plant species particularly within the realm of the toxicity and bioactivity. In conclusion, the plant extracts and active principles might be used in the near future as potential drugs to cure different ailments.
