English abstract
Objectives: We sought to evaluate the effectiveness of six weeks pulmonary
rehabilitation (PR) in patients with asthma-chronic obstructive pulmonary disease
(COPD) overlap syndrome (ACOS). Methods: We enrolled 28 patients with ACOS.
Fourteen patients were randomly allocated to the PR group, which comprised of
supervised endurance training, supervised resistance training, breathing exercises,
self management, and education. The other 14 patients were allocated to the control
group, who were asked to continue their usual routine strategies for six weeks. All
patients were assessed at baseline and after six weeks using the six minute walk test
(6MWT), St George Respiratory Questionnaire (SGRQ), pulmonary function test
(PFT), and Bode index (BI). Results: We saw a significant improvement in 6MWT
(p = 0.001), SGRQ (p = 0.007), and BI (p < 0.001) in the PR group after six weeks
compared to the control group. There was no significant difference between the groups
for PFT (p = 0.182) after six weeks. Conclusions: Use of a short-term PR program
in ACOS patients results in favorable changes in functional capacity, health-related
quality of life, and BI. However, short-term PR was not sufficient to register changes in
pulmonary function in these patients.
