English abstract
This article reports an uncommon cause of gastrointestinal
bleeding in a young male with uncorrected Tetralogy of Fallot
(TOF). This is the first reported instance of gastrointestinal
stromal tumor (GIST) causing bleeding in a patient with
uncorrected TOF. A 32-year-old Caucasian male with severe
developmental delay and uncorrected TOF presented with
black tarry stools. On admission, the patient was hypotensive
and tachycardic. He was successfully resuscitated with fluids
and blood transfusion. Upper gastrointestinal endoscopy was
performed and biopsy revealed GIST. It is interesting to note that
the patient survived till this age without any medical or surgical
treatment. This case presents GIST as a cause of gastrointestinal
bleeding in uncorrected TOF. Cytogenetic analysis revealed
deletion of short arm of chromosome 18. This case illustrates
that tyrosine kinase inhibitor may be an acceptable alternative
therapy to surgical resection.
