English abstract
Primary hyperaldosteronism (PA) is a common disease with a prevalence of 5–10%
in unselected patients with hypertension. Medullary nephrocalcinosis is a radiological
diagnosis and refers to diffuse calcification in the renal parenchyma. The three commonest
causes of nephrocalcinosis are hyperparathyroidism, distal renal tubular acidosis, and
medullary sponge kidney. PA is not a recognized cause of nephrocalcinosis. There are a
few case reports linking PA with nephrocalcinosis published till date. In this case series,
we report three cases where PA was possibly associated with medullary nephrocalcinosis.
In all three cases, the common causes of nephrocalcinosis were excluded by careful clinical
history, biochemical evaluation, and radiological findings. We conclude and emphasize
that a diagnosis of PA as an etiology of medullary nephrocalcinosis should be sought after
common causes have been excluded, at least in those with hypertension that is difficult
to control.
