English abstract
Irritable Bowel Syndrome (IBS) is a prevalent disease around the world. It is estimated that 10%-20% of the general population suffered from the disease, regards to standard scales like ROME II.1-3 It is about 2 times more prevalent in women compared to men and it is difficult differentiating from celiac disease. Celiac is a type of mal-absorption in small intestinal which is caused in genetically predisposed individuals exposed to gluten-contained regiment.1 Studies in European countries showed that more than 1% of general population has celiac disease.4,5 Recent advances in diagnostic methods and achievement to diagnostic tests with high sensitivity and specificity result in higher prevalence of the celiac disease than what was estimated before and can be presented with atypic or non-gastrointestinal symptoms. Symptoms of the disease can be similar to IBS, thus celiac patient may be treated as IBS. Recent studies have been reported increasing the prevalence of celiac in IBS patients compared to normal population.3