English abstract
The effect of drug on a person may be different than expected
because that drug interacts with another drug the person is taking
(drug-drug interaction), food, beverages, dietary supplements
the person is consuming (drug-nutrient/food interaction) or
another disease the person has (drug-disease interaction). A drug
interaction is a situation in which a substance affects the activity of
a drug, i.e. the effects are increased or decreased, or they produce a
new effect that neither produces on its own. These interactions may
occur out of accidental misuse or due to lack of knowledge about
the active ingredients involved in the relevant substances. Regarding
food-drug interactions physicians and pharmacists recognize
that some foods and drugs, when taken simultaneously, can alter
the body's ability to utilize a particular food or drug, or cause
serious side effects. Clinically significant drug interactions, which
pose potential harm to the patient, may result from changes in
pharmaceutical, pharmacokinetic, or pharmacodynamic properties.
Some may be taken advantage of, to the benefit of patients, but
more commonly drug interactions result in adverse drug events. Therefore it is advisable for patients to follow the physician and
doctors instructions to obtain maximum benefits with least fooddrug interactions. The literature survey was conducted by extracting
data from different review and original articles on general or
specific drug interactions with food. This review gives information
about various interactions between different foods and drugs and
will help physicians and pharmacists prescribe drugs cautiously
with only suitable food supplement to get maximum benefit for the
patient.
