English abstract
A22 year-old man from South
India presented with migraine with
aura and depression. Neurologically, he
demonstrated cognitive impairment, pseudobulbar
affect and bilateral pyramidal signs. The magnetic
resonance imaging (MRI) scan of his brain [Figure
1] showed increased FLAIR and T2 signals in the
bilateral anterior temporal and frontal white matter,
basal ganglia and external capsule. The clinical
features and the MRI finding of bilateral white
matter lesions in the anterior temporal pole and
external capsule, in the absence of hypertension and
optic nerve and spinal cord lesions, were diagnostic
of cerebral autosomal dominant arteriopathy with
subcortical infarcts and leukoencephalopathy
(CADASIL).1-
