Organophosphate (OP) pesticides inhibit both red blood cell (RBC) and plasma cholinesterases
(ChEs). Oximes, especially pralidoxime (2-PAM), are widely used as antidotes to treat OP poisoning. In
addition, N-acetylcysteine (NAC) is sometimes used as an adjuvant antidote. The current study aimed to assess
the feasibility of using NAC as a single therapeutic agent for OP poisoning in comparison to in vitro 2-PAM.