English abstract
The aerial parts of Pergularia tomentosa L. (Apocynaceae) collected from Oman were extracted by maceration using three solvents (Hexane, ethyl acetate, ethanol and their mixtures). Purification of hexane: chloroform (1:1), hexane: chloroform (4:1) and ethyl acetate fractions resulted in isolation of 3-acetyl lupeol (35), 3-acetyl a-amyrin (36), sitosterol-3-0-B-D-glucoside (37) respectively and a yet to be identified triacylglycerol (F-PT-22-comp 2). Their Structures were elucidated by spectroscopic methods (2D-NMR, R, and MALDI- TOF) and by comparison with literature data. Additionally, brine shrimp lethality assay showed that the crude extracts and some selected fractions from P. tomentosa were inactive at LC5o = 500 ug/mL.
