In carbon dioxide (CO2) capture process, Deep Eutectic Solvents (DESs) have been considered as an environmentally friendly alternative compared to conventional amine solvents. This study evaluated the CO2 solubility in an aqueous amine-based DES and compared to conventional Monoethanolamine solvent. It is necessary to develop a model that can predict the solubility of CO2 in complex DES mixtures, which can be used in designing CO2 capture processes. This study examined the CO2 solubility in aqueous amine-based DES mixtures, 9 Diethylenetriamine (DETA): 1 Ethanolamine hydrochloride (EAHC), using activity coefficient approach along with Peng-Robenson EoS, PR-UNIQUAC model. Regression analysis of VLE data of CO2 in DES was conducted using Aspen Plus simulator in order to determine the binary parameters of UNIQUAC method and the estimated results agree well with the experimental values. Equilibrium approach was utilized to simulate aqueous amine-based DES to remove CO2 from a shale gas feed. Then, a sensitivity analysis of the absorption column is studied using Aspen Plus and reported at different conditions. For instance, effect of solvent inlet temperature, varying number of equilibrium stages, solvent inlet flow rate, gas inlet flow rate and addition of water on the CO2 recovery. As wells as, heat of absorption of CO2 capture process was calculated using studied DES and compared to conventional amine solvents. In this work, the energy required to absorb 1 mole of CO2 is 9.6 kJ compared to MEA which required almost 80 kJ per mole of CO2. As well as, it was found from the simulation results, the recovery of decarbonized shale gas from studied DES is higher than conventional amine solvents. According to the comparison results, shows that aqueous amine based DESs are more effective in capturing CO2 because of their low volatility, high absorption capacity and lower energy usage. The CO2 capture process using an aqueous 9 DETA: 1 EAHC is a promising green alternative for CO2 removal processes.