وثيقة
Cerebro spinal fluid analysis in childhood bacterial meningitis.
المساهمون
Riaz, Ahmed S., مؤلف
Qasim, S., مؤلف
الناشر
Oman Medical Specialty Board.
ميلادي
2008-01
اللغة
الأنجليزية
الملخص الإنجليزي
Introduction: The aim of this study was to analyze the lumbar
puncture of all suspected cerebrospinal fluid (CSF) for suspected
meningitis.
Methods: This study was undertaken in the department of Child
Health, the Royal Hospital. The details of CSF of all files of the
children who had undergone lumbar puncture for suspected
meningitis from January 1, 2004 to December 31, 2004; were
enrolled for the study.
Results: A total of 395 lumbar punctures were done to exclude
bacterial meningitis. Out of the 142 CSF studies in neonates, 17
(12%) had the cytology suggestive of bacterial meningitis and 15
(88%) of them being culture positive. The commonest pathogen
was Group B Streptococcus (70%).The bacterial antigens were
positive only in 41% of the confirmed cases of bacterial meningitis,
all being that of Group B Streptococcus and gram stain positivity
in 45 percent of cases. In the 1- 3 months group all the 17 lumbar
punctures were normal. Of the 179 lumbar punctures done in 3-
18 months group, only 11(6%) were abnormal, 72% being culture
positive. Streptococcus pneumonia was the commonest organism
(88%). Bacterial antigens were positive only in 2 of the 8 culture
positive cases where gram stain was positive in 4 out of 8 cases.
Irritability, lethargy and sick looking appearance were present in
all the positive cases. None of the 28 children from 18 months to
5 years had abnormal CSF or positive CSF culture.
Conclusions: Based on the fact that only 7% of the 395 CSF
studies were abnormal, we conclude that better clinical judgment
and diagnostic criteria are warranted, before laying out guidelines
for lumbar puncture to confirm or exclude the diagnosis of
bacterial meningitis. Besides fever and convulsions as indicators
for CSF studies clinical parameters such as irritability, lethargy
and sick looking appearance are better indicators.
المجموعة
URL المصدر
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Thomas V, Riaz Ahmed S., & Qasim S.(2008). Cerebro Spinal Fvolumeluid Analysis in Childhood Bacterial Meningitis. Oman Medical Journal, 23 (1), 32-33.
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