This study amed to build a group Counseling Program in Reducing The Stress and Improving Self-confidence With Mothers of Children with Down Syndrome in Muscat Governorate –Seeb State. The researcher used the Semi- experimental opproach with One Group. The study used various tools gike the stress scale that is formed by Alshaks and Alsartawi(1996) and the researcher. After verifying the reliability and the stability of the study tools, the stress scale and the self confidence scale were applied in a sample of (10) mothers of children with Down Syndrome. The sample was chasen according to the inteional method from Muscat Governorate –Seeb State. After that, the group Counseling Program had been applied to the experimental sample in (15) sessions – (2) sessions per week. The researcher used SPSS statistics Program to analysis the sample resporser and the results were as follows: The results of calculating the arithmetical averages and the standard deviations showed that there are some statistical significe difference between the stress degree and the self- confidence degree wiancth the experimental sample indirduals on pre and post measurement showed higher degree as a result of applying the group Counseling Program in this study. Wilcoxon best results showed that are statistical significance difference at a level of 0.05 between the stress degree and the self- confidence degree with the experimental sample indirduals on pre and post measurement. The post measurement showed higher degree as a result of applying the group Counseling Program in this study.