Carbon dioxide (CO2) emissions are viewed as the main contributor to global warming. Therefore, CO2 capture technologies have become vital to mitigate the CO2 emissions. Recently, deep eutectic solvents (DESs) emerged among the several existing solvents, owing to their harmonizing qualities, low cost, high CO2 absorption, and being environmentally friendly. In this work, two different Eutectic Solvent (ES) with a common hydrogen bond acceptor of Imidazole (IM) and two different hydrogen bond donors, including diethylenetriamine (DETA) and tetraethylenepentamine (TEPA) were prepared with molar ratios of 1:1, 1:2, and 1:3. The prospect for CO2 loading in prepared ESs was studied experimentally using the drop pressure method at molar ratios of 1:1, 1:2, and 1:3, temperature ranging from 303.15K to 333.15K and pressure of 4 to 16 bar. The design of experiment (DOE) was applied to study the effect of independent variables that includes the pressure, temperature, and molar ratios on the CO2 loading of the solvents. The CO2 loading results were correlated based on response surface methodology (RSM) and analysis of variance (ANOVA). The results revealed that molar ratios, temperature, and pressure have a significant effect on the loading of CO2. The CO2 loading increased with increasing pressure and molar ratio, while decreased with increasing temperature. Similar trend was reported in the literature for several other solvents. Generally, IM:TEPA showed higher CO2 loading compared to IM:DETA. The maximum CO2 absorption in IM:DETA of 0.5115 (mol CO2/mol solvent) was observed at 303.15 K, 16 bar, and a 1:2 molar ratio, while the minimum CO2 loading was 0.1567 (mol CO2/mol solvent) at 313.15 K, 4 bar and a 1:1 molar ratio. However, the highest CO2 absorption in IM:TEPA was 0.5668 (mol CO2/mol solvent) at 303.15 K and 16 bar, with a 1:2 molar ratio, while the minimum CO2 loading of 0.1978 (mol CO2/mol solvent) was observed at 313.15K, 4 bar, and a 1:1 molar ratio. The Fourier transform infrared (FTIR) was used to identify the presence or absence of specific functional groups as well as the formation of the new functional group after the mixing. The results revealed that all functional groups of pure components were present in the spectra, and no new functional groups were observed, indicating the absence of chemical reactions. The CO2 loading of prepared Eutectic Solvents with a 1:2 molar ratio was further investigated with water content of 10, 20, 30, 40, and 50% volume% at temperature and pressure of 303.15 K and 16 bar respectively. The results showed that the water content had a significant effect on CO2 loading. It was remarkable to find that the introduction of water significantly boosted the CO2 loading in both studied systems. The physical properties, including density(ρ), viscosity(µ), and refractive index (nD), of IM:DETA and IM:TEPA were measured at atmospheric pressure with 1:1, 1:2, and 1:3 molar ratios and temperature ranging from 298.15 to 333.15K with a 5 K interval. The results obtained showed that the density and refractive index decrease directly with increasing temperature and molar ratio, while the viscosity decreases exponentially with increasing temperature. The density data of IM:DETA and IM:TEPA ranged between (1.0219-0.9607g/cc) and (1.0335-0.9779g/cc) respectively. The thermodynamic properties, including enthalpy, entropy, and Gibbs free energy, were calculated based on experimental data. The enthalpies of studied solvents were compared with those of MEA 30wt%. The results reveal that the proposed Eutectic Solvents required a lower regeneration energy.