The main aim of this research is to evaluate the Nitrogen removal performance to treat Natural gas from Oman North Gas Filed, assess the execution of utilizing this handle using Response Surface Methodology (RSM) combined with Central Composite Plan (CCD) which assess all the inter connections among working factors such as weight, temperature and stream rate to recognize the ideal operating conditions. Nitrogen Removal % in Production Gas and Reject gas in Flare Gas. Pressure and Flow Rate are the two main factors that improved the Nitrogen Removal % and Reject gas in Flare Gas removal while Temperature is the actual factor. The optimal conditions are a Pressure (750 psig), Temperature (125 F), Flow Rate (80 MMSCFD) in this method. Nitrogen removal % and reject gas in flare gas removal rates are 5.11 % and 8.522 %, respectively. Using Nitrogen Recovery Unit (NRU) and treating the natural gas with minimum inlet flow rate, the output result generates the procedure to be a different natural gas Processing treatment.