Columns at the first floor that are exposed to lateral vehicle impact puts the overall stability of the structure at serious risk. In most cases, column design does not consider such horizontal impact loads. The dynamic impact load will produce deflection, decrease the bearing capacity of the column, and may lead to the progressive collapse of the building. This study investigates the performance of steel column with axial load subjected to horizontal impact load from car accident using finite element modelling through LS-DYNA. A parametric study considering different impact scenarios are considered to evaluate the behavior of steel column under lateral car impact and the effectiveness of steel column protection system in reducing the effect of impact load due to vehicle impact. First numerical models are developed and validated against previous experimental data. Afterwards, an extensive parametric study is conducted to provide a comprehensive database of results covering different car mass, car velocity, boundary conditions, axial load ratio, impact directions, and column size. The outcomes of this research can help in understanding the behavior of axially loaded steel column under lateral impact. The parametric study shows that global buckling is the predominant failure mode, which was mainly dependent on the value of the kinetic energy of impact. Increasing axial load ratio, car mass, and car velocity lead to increase in the displacement on the column and higher probability to failure. The impact direction about minor axis has a lower impact resistance. In comparison to columns without axial loads, the steel column with axial loads exhibits more lateral deformation. Considering Reinforced Concrete (RC) encasement, leads to controlled local displacements, which has a positive impact on reducing the overall lateral deformation.