Nowadays, pharmacies are playing an incredibly important role in human development by improving the quality of life and reducing the time spent in the hospital. The accounting information system will enable the pharmacies to obtain accurate information about the type of the drug, quality, price, sales and inventory level at their stores. The aim of this study is to understand the private pharmacists’ perception on the use of Accounting Information system for inventory management and supply chain management and to know if AIS leads to improvement in operational efficiency of the pharmacies. Pharmacists perceive that AIS helps in maintaining safety stock levels, helps in monitoring the inventories, proper record is kept for damaged or problematic medical items, and helps in supply chain flexibility, responsibility, competency, and quickness in pharmacies. pharmacists think that inventory management and supply chain management using AIS is helping the improvement in the performance of pharmacies.