A retrospective study evaluating the prevalence of loss of smell, loss of taste and oral manifestations was carried out by framing an online questionnaire and dissemi nated among the health care workers including medical and dental students, who were aficted with COVID-19. The objective of this study was to fnd out the prevalence of the loss of smell, loss of taste (LOST) and oral manifestations and whether these (LOST & oral manifestations) can be the premonitory manifestations and also whether these can pre dict the prognosis of COVID-19 disease. Our study showed that the loss of smell, loss of taste and dry mouth did occur before the other symptoms considerably in the COVID-19 infected health workers. All the infected health workers were in home quarantine phase and not hospitalized during the occurrence of COVID-19. The loss of smell, loss of taste and oral manifestations can be the prodromal signs of COVID-19 and may be used as a screening tool to predict the severity of the disease.