الملخص الإنجليزي
Polycystic Ovarian Syndrome (PCOS) is a common and complex endocrine disorder predominantly affecting about one in twenty women of reproductive age. It is considered the most common cause of infertility in women.
Objective : To investigate anthropometric, biochemical characteristics, and nutritional and dietary patterns among women with PCOS compared to non-PCOS women as a control group.
Materials and Methods : In the-is case-control study, 100 women who were clinically-diagnosed with PCOS and 50 control PCOS women as controls using the 2003 Rotterdam criteria. For each participant, demographic anthropometric, biochemical and dietary intake were gathered by obtaining information from review of the hospital records at SQUH, laboratory assay, food frequency questionnaire and personal interviews with the participants. The two groups were compared and data analysis was conducted using SPSS program.
Results : There was no significant difference between the two means of age (P=0.64). Besides the age variable, the two groups were also matched regarding the education (P=0.14) and occupation (P=0.11). According to anthropometric measurement, there was no significant difference between the mean of the stature of the two groups (P = 0.54), but the mean of the waist circumference (P = 0.016), body mass index (P=0.002), weight (P=0.005) and WHR (P=0.001) were significantly higher in the PCOS group, compared to the control group. In dietary analysis, women with PCOS consumed more calories and carbohydrates but low dietary fiber than control Wome group (P=0.001, P= 0,001, and P= 0.001; respectively). PCOS group had a higher level of luteinizing hormone (LH) (P=0.001), fasting glucose (P=0.04), fasting insulin (P=0.001), and low high density lipoprotein (HDL) ) (P=0.01). The adjusted odds ratios (OR) obtained from logistic regression analysis indicated that PCOS was significantly associated with positive family history of PCOS and high intake of energy.
Conclusion : It is concluded that android obesity was a common feature and this abdominal obesity might be related to syndrome's complication. Regarding the dietary pattern and family history of PCOS, it was indicated that patients with PCOS had more positive family history of PCOS and consume more calories but low fiber and this might have been correlated to their disease.