The study aimed to develop a strategy to enhance the global competitiveness of higher education institutions in the Sultanate of Oman by exploring the current status of the main and supporting activities in higher education institutions using the value chain approach, and identifying the requirements and obstacles to achieving global competitiveness associated with the main and supporting activities in these institutions from the point of view of the study sample. In achieving its objectives, the study adopted mixed-methods design based on individual interviews with a sample of (20) higher education leaders, as well as a questionnaire administered to a sample of (261) members of the academic staff in higher education institutions. The results of the study showed that the infrastructure in higher education institutions needs further development to keep pace with the digital transformation and the rapid global developments. It has also been shown that there are deficiencies in the academic support services for faculty members, especially with regard to the exchange of experiences between faculty members in different universities. Moreover, more efforts need to be exerted to move from traditional teaching methods, and link education to industry and the labor market. With regard to scientific research, the results showed weak budgets related to scientific research, lack of research grants, and scarcity of data centers that contribute to providing researchers with statistics. The study came up with a proposed strategy based on the results of the reality analysis through the field study in the Omani context, using the value chain approach. The proposed strategy was based on some theoretical premises, and its dimensions consisted of the vision, mission, values, strategic directions, and goals aligned with Oman Vision 2040, the National Education Strategy 2040, and the dimensions of competitive advantage.