The study aims to highlight the most prominent effects of Brexit on the Britain-GCC relationship, by investigating the developments occurred in the security and economic aspects after the referendum‟s outcome in 2016 and drawing the future of this relationship. In addition, our goal is to track the evidence that indicates Britain's return to the region as one of the important alternatives to compensate its expected losses after Brexit, and the creation of permanent British bases in the GCC waters and funding institutions for British investment in the Gulf are examples of British return to the region. We relied on the qualitative method by using secondary sources such as books, articles published in scientific journals, master's and doctorate thesis. The study revealed that Britain will play a significant role in the GCC countries in terms of economic and security in the coming years; by assisting the GCC countries to achieve their future‟s visions which aim to dispense their economic dependence on oil revenue as well as enhance region‟s security. In return, the GCC countries will aid Britain to reduce the expected losses of Brexit by using their sovereign funds to invest in the United Kingdom. In fact, the GCC countries are welcoming the deep presence of Britain in the region since UK is a trusted ally to them. Consequently, in the future, Britain needs to guarantee its share of the huge projects that the GCC countries are planning, as well as playing a greater role in quelling the conflicts in the region. On the other hand, the GCC countries should maximize the benefit from British expertise in various sectors in order to achieve their future visions. It can be inferred that the future‟s relationship between the two parties will be "win, win" situation. Therefore, the two parties should further activate partnerships and reduce barriers in order to reach free trade agreements, as well as assisting each other to achieve their targets.