This study aimed to investigate the factors affecting the investment opportunities in the logistics sector in the special economic zone in Duqm. The study examined the relationship between logistic infrastructure, government regulation, macroeconomic environment and investment opportunities in the logistics sector in a special economic zone in Duqm. This paper provides both a framework and an analysis, which contributes to the further researches in the factors affecting the investment opportunities in the logistic sector in the special economic zone in Duqm and help the decision makers to make the right decision A primary and secondary data were used in this study. The secondary data was based on reviewing literature, and the primary method is distributing a questionnaire among employees and investors in the logistic sector in Duqm. The questionnaire was distributed through an electronic link via Google Forms and share it through social media applications. Three hundred five questionnaire responses were received. SPSS V26 program was used to test and analyze the collected data. The results show that the factors of logistic infrastructure, government regulation and macro-economic environment can affect investment opportunities in the logistics sector in The Special Economic Zone in Duqm. Duqm is on its way to becoming a global logistics hub. The Special Economic Zone in Duqm has to continue the infrastructure developments to match global standards and peer regions. Along with physical infrastructure developments, progress has been made in developing financial markets, improving the system of corporate governance, education and research related to logistics services that will significantly change the logistics landscape for the better. The limitations of this study, which may be taken into consideration on a similar study in the future, include more participants for the study to get more responses about the tested variables. The second limitation is the study and questionnaire was limited to only one special economic zone in Oman, and it will be more effective if it is applied to all economic zones in Oman. Key words: Logistics, investment, special economic zone in Duqm, logistic infrastructure, government regulation , macro-economic environment