Background: A striking feature of patients with cardiovascular disease is recurrent cardiovascular events.Previous studies found that the disease recurrence is linked to the job strain, C-Reactive Protein (CPR), hostility and the ensuing poor health behaviours. Uncontrolled diabetes is a common feature among those with repeated events of IHD. . Few studies have addressed such a concern in Middle Eastern countries. However, intriguing aspects of such conditionsis patients' knowledge about the risk factors for the disease. Objective: The current work was designed to characterize patients with recurrent episodes of ischemic heart disease in regards to health literacy, nutrition literacy, and other risk factors. Methods: The methodology followed in the present work was an inferential approach, using a cross-sectional design. Patients were recruited from Sultan Qaboos University Hospital based on a patient history of having an angiographically proven recurrence of Ischaemic Heart Disease (IHD). An interviewer-administered questionnaire was used to identify sociodemographic data, health literacy, and nutrition literacy. Serum levels of folate and vitamin B12 were also assessed. The internal consistency was checked at the pretesting stage. Univariate analysis was used to determine the differences of health and nutrition literacy in regards to sociodemographic and biochemical characteristics. Binary logistic regression was applied to identify the key determinants of health and nutrition literacy. Results: The majority of the participants were in their middle age (62%), and the frequency of the disease recurrence cases was noticed among men, married, and unemployed. The serum values of folate and vitamin B12 were found within the normal range among the patients. The education was statistically significantly associated with combined health and nutrition literacy (OR; 4.25, p = 0.02). Conclusion: My study provides a springboard for a new way to do characterization of patients with IHD recurrence in an Arabic-speaking country. Research into validating the currently established health and nutrition literacy tools in Arabic speaking regions is deferred to future work. Future prospective designed researches are needed to characterize those with a single episode against those with multiple episodes of IHD.