The world is witnessing an acceleration of changes and developments in various fields, and the Oman government has made great effort to encourage all Omanis to work to develop the economic liberalisation and modernisation in all sectors of the country. Purpose: assess the impact of Omanisation on small and medium enterprises (SMEs) in Oman, investigate the impact of Omanisation in the labour market, and examine the impact of governmental support for SMEs. Design and Methodology: This research adapted exploratory sequential approach to investigate the domain of this research. Hundred and six workers were invited to filled survey questionnaires, distributed via Google Drive document. SPSS software version 20 were used for data analysis using the descriptive and inferential statistics. Findings: Increased percentage of Omanisation in SMEs, increased number of workers in small and medium enterprises, existence of programmes to develop Omani competencies, impact of application of compulsory Omanisation and its consequences in the increase of customer complaints and the decrease in profits, decreased unemployment, significant impact of government support through encouraging and providing facilities and loans in implementing the Omanisation policy in SMEs. Keywords: Omanisation, small and medium enterprises, research, method, labour market, Oman, governmental support, SMEs.