Document
Primary hepatic lymphoma mimicking cholangiocarcinoma.
Identifier
DOI 10.5001/omj.2017.63
Contributors
Masoodi, Mohsen., Author
Kadivar, Maryam., Author
Publisher
Oman Medical Specialty Board.
Gregorian
2017-07
Language
English
Subject
English abstract
Primary hepatic lymphoma (PHL) presenting with obstructive jaundice is rare and can mimic a preoperative diagnosis of cholangiocarcinoma. We should consider PHL in patients with radiological hepatic disease with normal serum alpha-fetoprotein and carcinoembryonic antigen levels, and elevated lactate dehydrogenase. We present the case of a 67-year-old male with no significant medical history presented with abdominal pain, jaundice, fever, and abnormal liver function tests. Abdominal sonography and computed tomography scan suggested a diagnosis of obstructive jaundice and cholangitis due to cholangiocarcinoma (Klatskin tumor). A subsequent liver biopsy diagnosed PHL, and the patient was treated with combination chemotherapy, including rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP). PHL should be considered in patients presenting with biliary obstruction.
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Resource URL
Citation
Forghani, Foroogh., Masoodi, Mohsen, & Kadivar, Maryam (2017). Primary hepatic lymphoma mimicking cholangiocarcinoma. Oman Medical Journal, 32 (4), 335-338.
Category
Journal articles