Document
Vitamin D toxicity in adults : a case series from an area with endemic hypovitaminosis D.
Contributors
Publisher
Oman Medical Specialty Board.
Gregorian
2011-05
Language
English
Subject
English abstract
Vitamin D deficiency state is endemic to the Kashmir valley of the Indian subcontinent. Physicians often treat patients with high doses of vitamin D for various ailments and on occasion the prescribed doses far exceed the requirements of the patients. Ten cases of hypercalcemia due to vitamin D intoxication are presented with features of vomiting, polyuria, polydipsia, encephalopathy and renal dysfunction. All the patients had demonstrable hypercalcemia and vitamin D levels were high in nine of the 10 cases. The patients had received high doses of vitamin D and no other cause of hypercalcemia was identified. Treatment of hypercalcemia resulted in clinical recovery in nine cases. We conclude that hypervitaminosis D must be considered in the differential diagnosis of patients with hypercalcemia in endemically vitamin D deficient areas. A careful history and appropriate biochemical investigation will unravel the diagnosis in most of the cases.
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Citation
Koul, Parvaiz A., Ahmad, Sheikh Hilal, Ahmad, Feroze, Jan, Rafi A., Shah, S. U., & Khan, Umar H. (2011).Vitamin D toxicity in adults : a case series from an area with endemic hypovitaminosis D. Oman Medical Journal, 26 (3), 201-204.
Category
Journal articles