This study aims at identifying the level of effectiveness of employing the teaching methods based on the real evaluation in the development of scientific thinking in science for the seventh grade students. The study follows the semi-empirical approach. To achieve the objectives of this study, the researcher developed three tools: "teacher's guide that employs teaching methods based on the real evaluation", "Student activity book for the unit of pure substances, mixtures and solutions", and "Scientific thinking Test". The sample of the study consisted of (62) students and was randomly distributed to two groups: an experimental group of 31 students and a control group of 31 students. In order to answer the study questions, the researcher used the Cronbach Alpha Coefficient- to calculate the coefficient of the stability of the scientific thinking test, arithmetical averages, standard deviations, and Wilcoxon Signed Ranks to test hypotheses. The results of the study showed differences in the mathematical averages in the pre-test and the post-test of the experimental group in favor of the post-test. The value of mathematical average of the post-test for the experimental group (12.55), and the scientific methods based on the real evaluation in teaching science was more effective in the development of students' scientific thinking skills in the experimental group compared with the control group. The study concluded with a set of recommendations and proposals.