The study aimed to identify the adaptation of students with disabilities to university life at Sultan Qaboos University. I investigated the factors affecting their adaptation, the services and facilities provided by the university to students with disabilities, and their requirements for adaptation within the university. The study followed the descriptive analytical research design which was applied in a comprehensive social survey method. The instruments of the study were the questionnaire which they administered to (53) male and female students with disabilities studying at Sultan Qaboos University. The study found that the services provided by the Deanship of Student Affairs (Department of Students with Disabilities) were at high-level. It also found that the impact of personal factors affecting the adaptation of students with disabilities was very weak. Additionally, it found that the most important requirements were academic and administrative requirements among which were offering more majors for students with disabilities and providing them with more devices and modern technologies. They study concluded with some scientific suggestions to enhance the adaptation of students with disabilities at Sultan Qaboos University.