This study explores the feasibility of amoxicillin removal, via adsorption, from synthetic wastewater resembling pharmaceutical waste. Carbon nanotubes on powdered activated carbon substrate, that include potassium hydroxide, were synthesized using chemical vapor deposition method. The synthesized nanoparticles were then functionalized using nitric and sulfuric acid mixture to enable dispersion and better interaction with the targeted contaminant which was later used as adsorbent to remove amoxicillin from the aqueous solution. Characterization for the synthesized nanoparticles was conducted using Fourier transform infrared spectrum, x-ray diffraction, scanning electron microscopy and thermogravimetric analysis. The characterization results showed that carbon nanotubes were successfully fabricated. The results also exhibited that carbon nanotubes retained their structure after acidic treatment. In addition, surface characterization using FTIR results confirm the addition of oxygen containing group to the surface of the nanoparticles. Besides that, good crystallinity and thermal stability was achieved. In this work, pH, temperature, adsorbent dosage, contact time and stirring speed were investigated. It was found that the adsorption capacity has a proportional relationship with temperature highlighting the endothermic nature of the adsorption process. On the contrary, adsorption capacity was found to be inversely proportional to pH. Adsorption capacity decreased with the increase of adsorbent dosage but at the same time increase in adsorbent dosage leads to an increase in removal efficiency, so proper dosage selection requires considering both adsorption capacity and removal percent. However, stirring speed showed insignificant effect on the adsorption capacity with a slight improvement at high temperature. The results showed that functionalized nanoparticles pose high removal efficiency of amoxicillin in the aqueous solution with a maximum adsorption capacity of 357.14 mg/g once a model solution of 500 ppm amoxicillin concentration was used. The optimum conditions for kinetic, pH and temperature were found to be 6 hours, pH of 2 and temperature of 40 ˚C, respectively. While maximum adsorption capacity of 250 mg/g in 5 hours, at pH of 2 and temperature of 50 ˚C were obtained when a model solution of 100 ppm amoxicillin concentration was tested. Kinetic, isothermal, and thermodynamic models were also investigated during this study. The models revealed an endothermic nature of the adsorption process and formation of a monolayer of amoxicillin molecules in the adsorbent surface. The models suggests that chemisorption is the main adsorption mechanism. Further investigation on adsorbent regeneration and reusability showed that adsorbent was best regenerated using sodium hydroxide, the adsorbent maintained good adsorption capacity after two consecutive adsorption desorption experiment.