The study aimed to investigate the effectiveness of a career guidance program to develop some of the teamwork skills among grade eleven in North Al Batinah Governorate in Oman. The sample of the study consisted of 120 male and female students in grade eleven that was divided randomly into two groups. The experimental group consisted of 60 male and female students while the control group consisted of 60 male and female students, the experimental group exposed to the career guidance program, while the control group didn't expose to any treatment. The study adopted the quas-experimental method; the researcher used Teamwork Skills Scale after verifying its psychometric properties, which was taken from the study (Weng, 2000). The scale consisted of 38 statements divided into six dimensions; adaptability, communication, coordination, decision making, interpersonal, and leadership The results of the T-test showed differences between the average response of the members in the experimental group and the control group on all Teamwork Skills Scale dimensions in the post-experiment implementation of the experimental group, while the results of the same test showed differences with statistical significance between the average of the experimental group in pre and post implementation on all Teamwork Skills Scale dimensions in favor of the post implementiation. The results of two way ANOVA analysis showed statistically significance differences on the gender variable on some of the Teamwork Skills Scale dimensions in favor of male. The same results showed that the differences in performance with regard to the interaction effect between gender and group had no statistically significance differences. The results of the T-test showed also that there was no differences with statistical significance between the average of the experimental group in post and follow up implementation, on the all the scale dimensions. Impilications for the future research and recommendations were discussed.